| 11.12.20162016-12-11 15:15:00 | 15:15 | Premier League | 15. R | Southampton - Middlesbrough | -:- |
| 8.12.20162016-12-8 21:05:00 | 21:05 | Europa League Grp. K | 6. R | Southampton - Hapoel Beer Sheva | -:- |
| 3.12.20162016-12-3 16:00:00 | 16:00 | Premier League | 14. R | Crystal Palace - Southampton | 3:0 (2:0) |
| 30.11.20162016-11-30 20:45:00 | 20:45 | EFL Cup | 5. R | Arsenal - Southampton | 0:2 (0:2) |
| 27.11.20162016-11-27 17:30:00 | 17:30 | Premier League | 13. R | Southampton - Everton | 1:0 (1:0) |
| 24.11.20162016-11-24 19:00:00 | 19:00 | Europa League Grp. K | 5. R | Sparta Prag - Southampton | 1:0 (1:0) |
| 19.11.20162016-11-19 16:00:00 | 16:00 | Premier League | 12. R | Southampton - Liverpool | 0:0 (0:0) |
| 6.11.20162016-11-6 15:15:00 | 15:15 | Premier League | 11. R | Hull City - Southampton | 2:1 (0:1) |
| 10.12.20162016-12-10 18:30:00 | 18:30 | Premier League | 15. R | Leicester City - Manchester City | -:- |
| 6.12.20162016-12-6 20:45:00 | 20:45 | Champions League grp. C | 6. R | Manchester City - Celtic | -:- |
| 3.12.20162016-12-3 13:30:00 | 13:30 | Premier League | 14. R | Manchester City - Chelsea | 1:3 (1:0) |
| 26.11.20162016-11-26 13:30:00 | 13:30 | Premier League | 13. R | Burnley - Manchester City | 1:2 (1:1) |
| 23.11.20162016-11-23 20:45:00 | 20:45 | Champions League grp. C | 5. R | MGladbach - Manchester City | 1:1 (1:1) |
| 19.11.20162016-11-19 16:00:00 | 16:00 | Premier League | 12. R | Crystal Palace - Manchester City | 1:2 (0:1) |
| 5.11.20162016-11-5 16:00:00 | 16:00 | Premier League | 11. R | Manchester City - Middlesbrough | 1:1 (1:0) |
| 1.11.20162016-11-1 20:45:00 | 20:45 | Champions League grp. C | 4. R | Manchester City - Barcelona | 3:1 (1:1) |