| 11.12.20162016-12-11 17:30:00 | 17:30 | 1. Bundesliga | 14. R | Schalke 04 - Bayer Leverkusen | -:- |
| 7.12.20162016-12-7 20:45:00 | 20:45 | Champions League grp. E | 6. R | Bayer Leverkusen - Monaco | -:- |
| 3.12.20162016-12-3 15:30:00 | 15:30 | 1. Bundesliga | 13. R | Bayer Leverkusen - Freiburg | 1:1 (0:1) |
| 26.11.20162016-11-26 18:30:00 | 18:30 | 1. Bundesliga | 12. R | Bayern München - Bayer Leverkusen | 2:1 (1:1) |
| 22.11.20162016-11-22 18:00:00 | 18:00 | Champions League grp. E | 5. R | ZSKA Moskau - Bayer Leverkusen | 1:1 (0:1) |
| 18.11.20162016-11-18 20:30:00 | 20:30 | 1. Bundesliga | 11. R | Bayer Leverkusen - RasenBallsport Leipzig | 2:3 (2:1) |
| 5.11.20162016-11-5 15:30:00 | 15:30 | 1. Bundesliga | 10. R | Bayer Leverkusen - Darmstadt | 3:2 (1:0) |
| 2.11.20162016-11-2 20:45:00 | 20:45 | Champions League grp. E | 4. R | Tottenham Hotspur - Bayer Leverkusen | 0:1 (0:0) |
| 20.9.20162016-9-20 20:45:00 | 20:45 | EFL Cup | 3. R | Leeds United - Blackburn Rovers | 1:0 (0:0) |
| 23.8.20162016-8-23 20:45:00 | 20:45 | EFL Cup | 2. R | Blackburn Rovers - Crewe Alexandra | 4:3 (1:2) |
| 9.8.20162016-8-9 20:45:00 | 20:45 | EFL Cup | 1. R | Mansfield Town - Blackburn Rovers | 1:3 (0:1) |
| 21.2.20162016-2-21 15:00:00 | 15:00 | FA Cup | 5. R | Blackburn Rovers - West Ham United | 1:5 (1:2) |
| 30.1.20162016-1-30 16:00:00 | 16:00 | FA Cup | 4. R | Oxford United - Blackburn Rovers | 0:3 (0:2) |
| 18.1.20162016-1-18 20:15:00 | 20:15 | FA Cup | 3. R | Newport County - Blackburn Rovers | 1:2 (1:1) |