| 15.12.20162016-12-15 20:45:00 | 20:45 | KNVB Cup | 1/8 | Heracles - Sparta Rotterdam | -:- |
| 11.12.20162016-12-11 14:30:00 | 14:30 | Eredivisie | 16. R | FC Utrecht - Heracles | -:- |
| 2.12.20162016-12-2 20:00:00 | 20:00 | Eredivisie | 15. R | Heracles - NEC Nijmegen | 2:0 (1:0) |
| 27.11.20162016-11-27 14:30:00 | 14:30 | Eredivisie | 14. R | AZ Alkmaar - Heracles | 5:1 (3:0) |
| 19.11.20162016-11-19 18:30:00 | 18:30 | Eredivisie | 13. R | Heracles - Go Ahead Eagles | 2:1 (0:1) |
| 6.11.20162016-11-6 14:30:00 | 14:30 | Eredivisie | 12. R | Vitesse - Heracles | 1:2 (0:0) |
| 29.10.20162016-10-29 19:45:00 | 19:45 | Eredivisie | 11. R | Heracles - Sparta Rotterdam | 2:2 (0:1) |
| 26.10.20162016-10-26 20:00:00 | 20:00 | KNVB Cup | 2. R | Heracles - UNA | 5:0 (1:0) |
| 10.12.20162016-12-10 19:45:00 | 19:45 | Eredivisie | 16. R | PSV Eindhoven - Go Ahead Eagles | -:- |
| 6.12.20162016-12-6 20:45:00 | 20:45 | Champions League grp. D | 6. R | PSV Eindhoven - FC Rostov | -:- |
| 3.12.20162016-12-3 19:45:00 | 19:45 | Eredivisie | 15. R | Roda JC Kerkrade - PSV Eindhoven | 0:0 (0:0) |
| 26.11.20162016-11-26 19:45:00 | 19:45 | Eredivisie | 14. R | PSV Eindhoven - ADO Den Haag | 3:1 (1:0) |
| 23.11.20162016-11-23 20:45:00 | 20:45 | Champions League grp. D | 5. R | Atletico Madrid - PSV Eindhoven | 2:0 (0:0) |
| 19.11.20162016-11-19 19:45:00 | 19:45 | Eredivisie | 13. R | Willem II - PSV Eindhoven | 0:0 (0:0) |
| 5.11.20162016-11-5 19:45:00 | 19:45 | Eredivisie | 12. R | PSV Eindhoven - FC Twente | 1:1 (0:0) |
| 1.11.20162016-11-1 20:45:00 | 20:45 | Champions League grp. D | 4. R | PSV Eindhoven - Bayern München | 1:2 (1:1) |