| 10.12.20162016-12-10 19:45:00 | 19:45 | Eredivisie | 16. R | PSV Eindhoven - Go Ahead Eagles | -:- |
| 6.12.20162016-12-6 20:45:00 | 20:45 | Champions League grp. D | 6. R | PSV Eindhoven - FC Rostov | -:- |
| 3.12.20162016-12-3 19:45:00 | 19:45 | Eredivisie | 15. R | Roda JC Kerkrade - PSV Eindhoven | 0:0 (0:0) |
| 26.11.20162016-11-26 19:45:00 | 19:45 | Eredivisie | 14. R | PSV Eindhoven - ADO Den Haag | 3:1 (1:0) |
| 23.11.20162016-11-23 20:45:00 | 20:45 | Champions League grp. D | 5. R | Atletico Madrid - PSV Eindhoven | 2:0 (0:0) |
| 19.11.20162016-11-19 19:45:00 | 19:45 | Eredivisie | 13. R | Willem II - PSV Eindhoven | 0:0 (0:0) |
| 5.11.20162016-11-5 19:45:00 | 19:45 | Eredivisie | 12. R | PSV Eindhoven - FC Twente | 1:1 (0:0) |
| 1.11.20162016-11-1 20:45:00 | 20:45 | Champions League grp. D | 4. R | PSV Eindhoven - Bayern München | 1:2 (1:1) |
| 8.12.20162016-12-8 21:05:00 | 21:05 | Europa League Grp. G | 6. R | Panathinaikos - Celta Vigo | -:- |
| 24.11.20162016-11-24 19:00:00 | 19:00 | Europa League Grp. G | 5. R | Ajax - Panathinaikos | 2:0 (1:0) |
| 3.11.20162016-11-3 21:05:00 | 21:05 | Europa League Grp. G | 4. R | Panathinaikos - Standard Lüttich | 0:3 (0:0) |
| 20.10.20162016-10-20 19:00:00 | 19:00 | Europa League Grp. G | 3. R | Standard Lüttich - Panathinaikos | 2:2 (1:2) |
| 29.9.20162016-9-29 19:00:00 | 19:00 | Europa League Grp. G | 2. R | Celta Vigo - Panathinaikos | 2:0 (0:0) |
| 15.9.20162016-9-15 21:05:00 | 21:05 | Europa League Grp. G | 1. R | Panathinaikos - Ajax | 1:2 (1:1) |
| 25.8.20162016-8-25 19:00:00 | 19:00 | Europa League Qualification | Finale | Broendby IF - Panathinaikos | 1:1 (1:0) |